Abstract #1740

Proof-of-principal of 1H PREFUL approaches at 0.5T: lung ventilation and perfusion maps of a healthy volunteer and a Covid-19 survivor

Arthur Harrison¹, Galina E Pavlovskaya^1,2, Thomas Meersmann¹, Olga S Pavlova^3,4, Alexander Makurenkov⁴, Yury A Pirogov⁴, and Nikolay V Anisimov^3,4

¹SPMIC/Medicine, University of Nottingham, Nottingham, United Kingdom, ²2Nottingham NIHR Biomedical Research Centre, Nottingham, United Kingdom, ³Faculty of Fundamental Medicine, Lomonosov Moscow State University, Moscow, Russian Federation, ⁴Faculty of Physics, Lomonosov Moscow State University, Moscow, Russian Federation

The ability to visualise non-invasively impaired lung ventilation and perfusion caused by lung scarring is important in monitoring recovery of Covid-19 survivors. The hp Xenon-129 imaging modality is currently approved for clinical use in the UK only, however, it has been shown recently that 1H PREFUL methodology can be used to visualise lung perfusion and ventilation in health and disease at 3T whole body scanners. However, 3T scanners may not be available for healthcare in countries with low and middle income, hence PREFUL at 0.5T was used to assess lung ventilation and perfusion in health and Covid-19 disease.

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