Abstract #1671

Power spectral density of salience network alterations in obsessive-compulsive disorder: Impact on thought-action fusion performance

Eunji Kim¹, Sang Won Lee², Hyunsil Cha¹, Heajung Choi¹, Seungho Kim¹, Yunheung Kim³, Seung Jae Lee², and Yongmin Chang⁴

¹Medical & Biological Engineering, Kyungpook National University, Daegu, Korea, Republic of, ²Psychiatry, Kyungpook National University Hospital, Daegu, Korea, Republic of, ³Kyungpook National University, Daegu, Korea, Republic of, ⁴Radiology and Molecular Medicine, Kyungpook National University, Daegu, Korea, Republic of

Obsessive-compulsive disorder (OCD) showed the functional connectivity alterations in default mode network (DMN), central executive network (CEN) and salience network (SN)¹. We investigated the difference of intrinsic networks between OCD and healthy controls (HC) from thought-action fusion (TAF) task and resting state by using fMRI. During TAF task, Power spectral density (PSD) of SN in OCD showed lower than PSD in HC in low-frequency bins. PSD of SN showed a significant correlation with TAF score and OBQ scale in OCD. Therefore when doing TAF task, OCD symptoms might have relations with alterations of PSD of SN.

This abstract and the presentation materials are available to members only; a login is required.

Join Here