Abstract #0753

Free-Breathing Liver Fat and R2* Mapping: Multi-Echo Radial FLASH and Model-based Reconstruction (MERLOT)

Zhengguo Tan^1,2, Sebastian Rosenzweig^1,2, Xiaoqing Wang^1,2, Nick Scholand^1,2, H Christian M Holme^1,2, Moritz Blumenthal¹, and Martin Uecker^1,2,3,4

¹Institute for Diagnostic and Interventional Radiology, University Medical Center Göttingen, Göttingen, Germany, ²German Center for Cardiovascular Research (DZHK), Göttingen, Germany, ³Cluster of Excellence "Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells" (MBExC), University of Göttingen, Göttingen, Germany, ⁴Campus Institute Data Science, University of Göttingen, Göttingen, Germany

To achieve free-breathing liver fat and $$$R_2^\star$$$ mapping, this work combines multi-echo radial FLASH with stack-of-stars volumetric acquisition and SSA-FARY to resolve respiratory motion. Moreover, regularized model-based reconstruction is implemented in BART to directly estimate quantitative parameter maps from acquired k-space data. Joint spatial and temporal regularization is used in this work. The proposed method is validated with NIST and water/fat phantoms. Furthermore, free-breathing liver studies show repeatability and good agreement between single-slice real-time and volumetric acquisition.

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