Abstract #0629

Highly Accelerated Sub-millimeter Resolution 3D EPI using Variable Density CAIPI Sampling with Temporal Random Walk for Functional MRI at 7 Tesla

Suhyung Park^1,2, Sugil Kim³, Hankyeol Lee⁴, Seulgi Eun⁴, Seong-Gi Kim^4,5, and David Feinberg^6,7

¹Department of Computer Engineering, Chonnam National University, Gwangju, Korea, Republic of, ²Department of ICT Convergence System Engineering, Chonnam National University, Gwangju, Korea, Republic of, ³Siemens-Healthineers, Seoul, Korea, Republic of, ⁴Center for Neuroscience Imaging Research (CNIR), Institute for Basic Science (IBS), Suwon, Korea, Republic of, ⁵Department of Biomedical Engineering, Sungkyunkwan University, Suwon, Korea, Republic of, ⁶University of California, Berkeley, Berkeley, CA, United States, ⁷Advanced MRI Technologies, Sebastopol, CA, United States

With ultra-high fields, 3D EPI has been used by improving imaging efficiency. Nevertheless, there have been some limitations: 1) the regular sampling limits the use of temporal structure in the data and 2) parallel imaging allows up to 6-fold acceleration in 3D acquisition. Here, we developed an accelerated 3D EPI using VD-CAPI sampling with temporal random walk. Experimental studies confirm advantages in acceleration, SNR, and sensitivity of the proposed method: 1) temporal random walk allows extra spatial encoding across time, 2) temporal prior provides high SNR, and 3) the temporal incoherent sampling and high SNR result in higher BOLD activations.

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