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Abstract #0628

Disposable Point-of-care Portable Perfusion Phantom for Accurate Quantitative DCE-MRI

Martin Dawson Holland1, Andres Morales1, Sean Simmons2, Brandon Smith1, Samuel R Misko1, Roy P Koomullil1, Junzhong Xu3, David A Hormuth, II4, Junzhong Xu3, Thomas E Yankeelov4, and Harrison Kim1
1University of Alabama at Birmingham, Birmingham, AL, United States, 2Objective Design, Birmingham, AL, United States, 3Vanderbilt University Medical Center, Nashville, TN, United States, 4University of Texas, Austin, TX, United States

A new point-of-care portable perfusion phantom was developed to reduce inter- and intra-scanner variability of quantitative dynamic contrast enhanced magnetic resonance imaging (DCE-MRI). This device is disposable, easily operable, and conveniently deliverable for widespread, routine clinical use. As this device has high repeatability (intraclass correlation coefficient = 0.997), it can be utilized to improve the accuracy of quantitative DCE-MRI based analysis of many diseases including cancer.

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