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Abstract #0295

Towards differentiation of white matter pathologies through B-tensor encoding.

Ricardo Rios-Carrillo1, Ricardo Coronado-Leija2, Hiram Luna-Munguía1, Alonso Ramírez-Manzanares3, and Luis Concha1
1Instituto de Neurobiología, Universidad Nacional Autónoma de México, Querétaro, Mexico, 2Radiology, New York University School of Medicine, New York, NY, United States, 3Centro de Investigación en Matemáticas, Guanajuato, Mexico

This work explores the ability of B-tensor encoding methods to disentangle axonal degeneration and inflammation through DW-MRI. In particular, we tested Q-space trajectory encoding and diffusion tensor distribution imaging. Both methods clearly differentiated between damaged and intact nerves, and showed moderately different diffusion characteristics between the two experimental conditions.

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