Abstract #0260

Dermal sodium space in controls and Type 2 Diabetes Mellitus patients characterised at histological length scales using 1H/23Na MRS and MRI at 9.4T

Galina E Pavlovskaya^1,2, Christopher J Philp¹, Thomas Meersmann¹, Petra Hanson^3,4, Harpal S Randeva^4,5, Paul Paul O’Hare^4,5, and Thomas Barber^4,5

¹SPMIC/Medicine, Univeristy of Nottingham, Nottingham, United Kingdom, ²4Nottingham NIHR Biomedical Research Centre, Nottingham, United Kingdom, ³Warwick Medical School, University of Warwick, Warwick, United Kingdom, ⁴2Warwickshire Institute for the Study of Diabetes Endocrinology and Metabolism, University Hospitals Coventry and Warwickshire, Coventry, United Kingdom, ⁵Warwick Medical School, University of Warwick, Coventry, United Kingdom

We reveal intriguing experimental results providing the evidence for dermal space storage for sodium, and how dynamics of the space changes in patients with Type2 Diabetes Mellitus.

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