Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system. MR Elastography (MRE) can quantitatively measure biomechanical tissue properties in vivo noninvasively. In this study, we investigated the potential value of MRE for the evaluation of centrum ovale viscoelasticity (including shear stiffness, storage modulus, shear loss modulus, and damping ratio) in Southern Chinese MS patients and to try to analyze its relevance to clinical manifestations. Our results showed that only the damping ratio of the centrum ovale was significantly decreased in MS patients and may provide a potential quantitative biomarker to evaluate MS.
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