Fluorine-19 (19F) MRI is an established tool for tracking inflammatory cells in vivo due to its excellent detection specificity. Nonetheless, low signal-to-noise ratios remain a major challenge, especially when studying inflammatory cell distribution in the brain. It was shown that compressed sensing (CS) increases 19F MRI sensitivity, yet prospective undersampling using dedicated CS sequences has only been reported in proof of concept experiments. Since false positives were observed in CS reconstructions, this work provides a thorough assessment of detection performance of in vivo CS as a tool for enhancing 19F MRI sensitivity.
This abstract and the presentation materials are available to members only; a login is required.