Abstract #2462

Non-invasive assessment of progressive changes in aristolochic acid (AA) induced AKI with T2 mapping

Yingjie Mei^1,2, Guixiang Yang³, Yihao Guo^1,4, Kaixuan Zhao^1,4, Chenggong Yan³, Yikai Xu³, and Yanqiu Feng^1,4

¹Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, Guang Zhou, China, ²Philips Healthcare, Guang Zhou, China, ³Department of Medical Imaging Center, Nanfang Hospital, Southern Medical University, Guangzhou, China, ⁴School of Biomedical Engineering, Southern Medical University, Guang Zhou, China

Cases of Aristolochic acid nephropathy (AAN) have been reported worldwide, yet no serum or urinary biomarkers have been shown to have clinical utility in detection of AAN. In this study, we aim to detect renal changes in the early phase of AAN with T2 mapping. The results suggest that T2 mapping may be a valuable tool in experimental studies and clinical practice of acute phase of AAN.

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