Here we propose a unique perfusion acquisition that applies a 2D/3D alternating acquisition method to obtain 2D simultaneous multi-slice (SMS) and 3D stack-of-stars (SoS) data every other heartbeat. Within each heartbeat, 2D SMS and 3D acquisitions are performed following a saturation pulse. Potential advantages include different spatio-temporal resolution and artifacts, accurate AIF acquisitions and the ability to compare the sequences directly with a single injection. Preliminary quantitative results of 7 dog and 3 human studies show the promise of this approach.
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