Abstract #2088

Pancreatic iron and cardiac iron and function in patients with thalassemia intermedia

Antonella Meloni¹, Laura Pistoia¹, Vincenzo Positano¹, Giuseppe Peritore², Paolo Preziosi³, Ada Riva⁴, Massimiliano Missere⁵, Antonino Vallone⁶, Valentina Carrai⁷, F. Mehtap Pasin³, Mauro Murgia⁸, and Alessia Pepe¹

¹MRI Unit, Fondazione G. Monasterio CNR-Regione Toscana, Pisa, Italy, ²"ARNAS" Civico, Di Cristina Benfratelli, Palermo, Italy, ³Ospedale "Sandro Pertini", Roma, Italy, ⁴Ospedale “SS. Annunziata” ASL Taranto, Taranto, Italy, ⁵Fondazione di Ricerca e Cura "Giovanni Paolo II", Campobasso, Italy, ⁶Azienda Ospedaliera "Garibaldi" Presidio Ospedaliero Nesima, Catania, Italy, ⁷Universitaria Careggi, Firenze, Italy, ⁸Ospedale San Martino di Oristano, Oristano, Italy

In patients with thalassemia intermedia (TI) pancreatic iron overload is frequent (58.1%), especially if regular transfusions are performed. Pancreatic T2* values were correlated with cardiac T2* values and a normal pancreas T2* showed negative predictive value of 100% for cardiac iron. Global pancreas T2* values were not correlated to biventricular volumes and ejection fraction or to myocardial fibrosis.

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