Abstract #1842

The performance of mean-apparent-propagator diffusion model in assessing brain parenchymal microstructure changes of hypertensive patients

shenghui Xie¹, shaoyu Wang², xu Yan², huapeng Zhang², guang Yang³, and yang Gao¹

¹Department of radiology, affiliated hospital of Inner Mongolia medical university, Hohhot, China, ²MR Scientific Marketing, Shanghai, China, ³Shanghai Key Laboratory of Magnetic Resonance, Shanghai, China

The purpose of this study was to evaluate the value of diffusion spectrum imaging (DSI) MAP diffusion model in the changes of brain tissue microstructure in patients with primary essential hypertension, as well as the differences of various parameters including RTOP, RTAP, RTPP, QIV and MSD between the hypertensive group and the normal control group. The results showed that there were significant differences between RTOP and QIV. All the MAP-MRI parameters showed obvious differences in detecting the changes of brain structure microstructure in the early stage of hypertension, especially the RTOP and QIV parameters.

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