The Virtual Brain(TVB) has been developed to simulate brain dynamics starting from individual structural and functional connectivity(FC) MRI data. Nowadays, only cerebrocortical circuits have been considered. Here, we provided the first TVB simulations including cerebellar nodes on single-subject datasets. The brain dynamics simulated by either including or excluding cerebrocortical-cerebellar connectivity were compared, revealing that the predictive power of empirical FC is not significantly modified by inclusion of cerebro-cerebellar loops. To improve the present results and apply this pipeline to predict disease states involving cerebrocortical-cerebellar loops, specific neural mass models accounting for cerebellar microcircuit physiology need to be integrated in TVB.
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