Abstract #1708

Comparative evaluation of Oligodendroglioma and Astrocytoma subtypes with similar grade using Conventional MRI and T1 perfusion MRI imaging

Mamta Gupta¹, Abhinav Gupta¹, Anup Singh², Jitender Saini³, Rana Patir⁴, Sunita Ahlawat⁵, Vani Santosh³, Neha Vats², Manish Awasthi², Suhail Parvaze⁶, and Rakesh Kumar Gupta¹

¹Department of Radiology, Fortis Memorial Research Institute, Gurgaon, India, ²Centre for Biomedical Engineering, Indian Institute of Technology, New Delhi, India, ³National Institute of Mental, Health and Neurosciences, Bangalore, India, ⁴Department of Neurosurgery, Fortis Memorial Research Institute, Gurgaon, India, ⁵SRL Diagnostics, Fortis Remorial Research Institute, Gurgaon, India, ⁶Philips Innovation Campus, Bangalore, India

The differentiation of oligodendroglioma and astrocytoma has become increasingly important due to the distinct sensitivity of oligodendroglioma (OD) to chemotherapy and prolonged survival compared to astrocytoma (AT) of similar grades. The purpose of the present study was to determine whether unique characteristics of OD and AT are visible on MR imaging and to assess the added value of perfusion imaging in differentiating OD from AT tumors across similar grades in large study population. Our results demonstrated no characteristic/specific conventional MRI features and perfusion parameters those could clearly differentiate similar grades of OD’s and AT tumors.

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