Abstract #1619

Correlation analysis between APTW and blood flow status in the ischemic penumbra of patients with subacute ischemic stroke

Yuhan Jiang¹, Yanwei Miao¹, Liangjie Lin², Zhiwei Shen², Peipei Chang¹, Yiwei Che¹, Ailian Liu¹, Qingwei Song¹, and Jiazheng Wang²

¹the First Affiliated Hospital of Dalian Medical University, Dalian, China, Dalian, China, ²Philips Healthcare, Beijing, China, Beijing, China

The presence, dynamic evolution, and outcome of the ischemic penumbra (IP) are important for the choice of treatment options and prognosis. At present, there is currently no study to combine the APTw MRI with the blood flow measurements for IP analyses. Purpose of this study was to analyze the association between APT metabolic changes and blood flow status in the IP of patients with subacute infarction in the unilateral middle cerebral artery by APT and ASL techniques. Significant correlations of APTw values to CBF values of PLD1.5.

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