Abstract #1191

Detection of radiation brain injury in patients with nasopharyngeal carcinoma: A comparative study of DTI, DKI and MAP-MRI

Weike Zeng¹, Mengzhu Wang², Yaxuan Pi³, Yi Li³, Xu Yan⁴, Guang Yang⁵, and Jun Shen⁶

¹Deptpartment of Radiology, SUN YAT-SEN Memorial Hospital, SUN YAT-SEN University, Guangzhou, China, ²MR Scientific Marketing, Siemens Healthcare, Guangzhou, China, ³department of NEUROLOGY, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China, ⁴MR Scientific Marketing, Siemens Healthineers, Shanghai, China, ⁵Shanghai Key Laboratory of Magnetic Resonance, East China Normal University, Shanghai, China, ⁶Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China

Mean apparent propagator (MAP)-MRI, which builds a powerful analytical framework based on the random motion distribution of real water molecules, can more accurately and comprehensively characterize microstructure features of brain tissues than conventional diffusion imaging. This study investigated the application of MAP-MRI in the early diagnosis of radiation-induced brain injury in patients with nasopharyngeal carcinoma, compared with diffusion tensor imaging (DTI) and diffusion kurtosis imaging (DKI).

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