Abstract #1085

Decoding the Effects of Rhythm on Hemodynamics in Patients with Atrial Fibrillation Using a 5D Flow Framework

Liliana Ma^1,2, Jerome Yerly³, Lorenzo Di Sopra³, Davide Piccini^3,4, Rod Passman⁵, Philip Greenland⁵, Daniel Kim^1,2, Matthias Stuber³, and Michael Markl^1,2

¹Department of Radiology, Northwestern University, Feinberg School of Medicine, Chicago, IL, United States, ²Department of Biomedical Engineering, Northwestern University, Evanston, IL, United States, ³Department of Radiology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland, ⁴Siemens Healthcare, Lausanne, Switzerland, ⁵Department of Medicine and Preventive Medicine, Northwestern University, Feinberg School of Medicine, Chicago, IL, United States

Atrial fibrillation (AF) is the most common cardiac arrhythmia and is associated with increased risk of ischemic stroke. Arrhythmic heartbeats in AF may alter atrial flow characteristics and the influence of differences in heart rates on LA 3D hemodynamics has not yet been systematically investigated. Recently, a fully self-gated free-running 5D flow (4D flow+respiration) framework was introduced and validated. The purpose of this study was to expand the 5D flow framework to explore the influence of heart rates on thrombogenic hemodynamic parameters in AF patients.

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