Hyperpoalrized 13C urea T2 relaxometry has been previously used to assess the diabetic and ischemic kidney. In this study we utilise a novel fitting method (Laplacian) to visualise the extent of damage, through a reduction in bi-exponential relaxation behaviour, in a rodent model of renal ischemia.
This opens up a number of potential pre-clinical and clinical uses of hyperpoalrized 13C urea imaging providing a novel, and useful, readout of renal ischemia.
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