Abstract #0575

Post-NAC evaluation using ultrafast breast dynamic contrast-enhanced MRI

Maya Honda¹, Masako Kataoka¹, Mami Iima¹, Kanae Kawai Miyake¹, Akane Ohashi¹, Ayami Ohno Kishimoto¹, Rie Ota¹, Marcel Dominik Nickel², Tatsuki Kataoka³, Masakazu Toi⁴, and Kaori Togashi¹

¹Department of Diagnostic Imaging and Nuclear Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan, ²MR Application Predevelopment, Siemens Healthcare GmbH, Erlangen, Germany, ³Department of Diagnostic pathology, Graduate School of Medicine, Kyoto University, Kyoto, Japan, ⁴Department of breast surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan

The study evaluated the accuracy to predict pathologic complete response (pCR) after neo-adjuvant chemotherapy (NAC) using ultrafast dynamic contrast-enhanced (UF-DCE) MRI. The sensitivity to predict pCR was higher on UF-DCE MRI compared with conventional dynamic contrast-enhanced (DCE) MRI. The difference in image and pathological sizes on UF-DCE MRI was smaller than on conventional DCE MRI. UF-DCE MRI potentially assesses post-NAC status in breast cancer patients accurately in a shorter acquisition time.

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