Abstract #0530

Synthetic T1rho dispersion imaging for improved myocardial tissue characterization using dispersion reconstruction

Maximilian Gram^1,2, Daniel Gensler^1,3, Patrick Winter^1,2, Michael Seethaler^2,3, Peter Jakob², and Peter Nordbeck^1,3

¹Department of Internal Medicine I, University Hospital Würzburg, Würzburg, Germany, ²Experimental Physics 5, University of Würzburg, Würzburg, Germany, ³Comprehensive Heart Failure Center (CHFC), University Hospital Würzburg, Würzburg, Germany

T_1ρ dispersion imaging is a very time-consuming process because full T_1ρ-mapping at different spin-lock amplitudes is required. Due to this issue, investigation of T_1ρ dispersion is hardly feasible in the limited measurement time of a small animal experiment. In this work, we present a novel approach for the rapid measurement of cardiac T_1ρ dispersion called dispersion reconstruction. With our new concept a T_1ρ dispersion image is generated by only acquiring a fraction of the required mapping data. Phantom and in vivo experiments confirm the applicability of our new method as part of a conventional protocol for small animal studies.

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