Abstract #0262

Accelerated T2 Mapping of the Lumbar Intervertebral Discs: Robust Quantification in Clinically Feasible Acquisition Times

Marcus Raudner¹, Markus Schreiner^1,2, Tom Hilbert^3,4,5, Tobias Kober^3,5,6, Anna Szelenyi⁷, Vladimir Juras¹, and Siegfried Trattnig¹

¹High Field MR Centre, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria, ²Department of Orthopedics and Trauma Srugery, Medical University of Vienna, Vienna, Austria, ³Advanced Clinical Imaging Technology, Siemens Healthcare, Lausanne, Switzerland, ⁴Department of Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland, ⁵LTS5, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, ⁶Department of Radiology, University Hospital and University of Lausanne, Lausanne, Switzerland, ⁷Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria

The physiological biochemical state of the intervertebral disc (IVD) allows for passive water-storing capabilities because of a high concentration of glycosaminoglycans (GAG) and an inherent structural integrity. T₂ mapping can quantitatively assess the IVD’s water content and GAG concentration, but a typical 2D multi echo spin echo (MESE) sequence suffers from clinically prohibitive scan times. To resolve this, we compared the MESE sequence against GRAPPATINI, an accelerated sequence combining parallel imaging and a model-based reconstruction for T₂ quantification which uses undersampling to shorten the scan time from 13:18 to 2:27 minutes.

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