Abstract #4143

Multi-breath Wash-in Hyperpolarized 129Xenon MRI in Human Subjects

Hooman Hamedani¹, Ryan Baron¹, Stephen Kadlecek¹, Kai Ruppert¹, Ian Duncan¹, Yi Xin¹, Francisca Bermudez¹, Sarmad Siddiqui¹, Mehrdad Pourfathi¹, Faraz Amzajerdian¹, Luis Loza¹, Tahmina Achekzai¹, Federico Sertic¹, and Rahim R. Rizi¹

¹Radiology, University of Pennsylvania, Philadelphia, PA, United States

We have shown the feasibility of multi-breath wash-in imaging of regional fractional ventilation using HP ¹²⁹Xe MRI for the first time in both healthy and diseased human subjects.

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