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Abstract #3381

Fibre Tracking of the Arcuate Fasciculus at High Spatial and Angular Resolution

Matthew Lyon1, Thomas Welton1, Jerome Maller1,2, MyungHo In3, Ek Tsoon Tan4, Matt Bernstein3, Erin Gray3, Yunhong Shu3, John III Huston3, and Stuart Grieve1,5

1Sydney Translational Imaging Laboratory, Heart Research Institute, The University of Sydney, Sydney, Australia, 2GE Healthcare, Melbourne, Australia, 3Department of Radiology, Mayo Clinic, Rochester, MN, United States, 4GE Global Research, Niksayuna, NY, United States, 5Department of Radiology, Royal Prince Alfred Hospital, Sydney, Australia

We compared fibre tracking performance in the arcuate fasciculus across a range of angular resolutions, as well as a low distortion dataset using diffusion MRI data from a Compact 3T scanner with high-performance gradients. Tracking performance increased approximately linearly with greater angular resolution. Performance was also improved using a low-distortion diffusion sequence at a single relatively low angular resolution acquisition (33 directions).

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