Abstract #2851

The comparison of L-FBPA PET/MR and PET/CT for BNCT treatment evaluation

Yi-Wen Lo¹, Ko-Han Lin¹, Yi-Wei Chen², Rong-Hong Jhou¹, Chien-Ying Li¹, Li-Chen Shen³, Bang-Hung Yang ¹, Chi-Wei Chang¹, and Wen-Sheng Huang¹

¹Department of Nuclear Medicine, Taipei Veterans General Hosptial, Taipei City, Taiwan, ²Department of Radiation Oncology, Taipei Veterans General Hosptial, Taipei City, Taiwan, ³Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei City, Taiwan

We hypothesized that o-fluoro-L-p-boronophenylalanine (L-¹⁸FPBA) PET/MR could provide more precise treatment planning for Boron neutron capture therapy (BNCT) compared with L-¹⁸FBPA PET/CT. We implemented the phantom trial to measure the radioactivity correlation between PET/CT and PET/MR. Results have high comparability. We accessed patients who were potentially eligible for BNCT with same paradigms. The initial results represented acceptable correlation between these two modalities. Furthermore, because of high sensitivity and sophisticated imaging resolution, medics can easy to organize the more accurate treatment planning. In conclusion, PET/MR provides comparable L-¹⁸FBPA quantitative measurement and more diagnostic accuracy than PET/CT.

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