Two exploratory radiomics segmentation algorithms in T2-weighted imaging analysis for predicting apical positive surgical margins of prostate cancer: A pilot study

SynopsisThis retrospective study aims to compare the two different segmentation algorithms of radiomics analysis for predicting the apical surgical margin (SM) status before radical prostatectomy (RP). Preoperative prostate MR scans were performed for 76 enrolled patients and T2-weighted images was assessed by a radiomics model, using two different delineating methods: including the surrounding tissues of the targeted lesions or not. Finally 152 bilateral surgical margins’ status (training dataset: n = 110, testing dataset: n = 38) were evaluated. The result demonstrated the segmentation algorithms were comparable, of which the new method might reduce the delineation work for future radiomics research.