Abstract #1218

Click Your Fat Away: Rapid Synthetic Knee MR Imaging with Switchable Fat and Magnetization-Transfer Contrast

Tom Hilbert^1,2,3, Jan Fritz⁴, Patrick Omoumi², José P. Marques⁵, Emilie Mussard^1,2,3, Jean-Philippe Thiran^2,3, Reto Meuli², and Tobias Kober^1,2,3

¹Advanced Clinical Imaging Technology, Siemens Healthcare AG, Lausanne, Switzerland, ²Department of Radiology, University Hospital (CHUV), Lausanne, Switzerland, ³LTS5, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland, ⁴Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, United States, ⁵Radboud University Nijmegen, Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Netherlands

Synthetic MRI is increasingly used in clinical practice to supplement or replace conventional MRI, due to the ability to generate both a multitude of MR images with weighted contrasts and quantitative T1, PD and T2 maps, which is of high interest in musculoskeletal imaging. To further broaden the application of synthetic image contrasts, we developed a method which allows switching between images with and without fat signal as well as magnetization-transfer weighting. The method includes three pulse sequences to estimate quantitative maps for the calculation of a variety of contrasts and requires a total acquisition time of 6:46 min.

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