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Abstract #1058

Multilevel functional organization of the mouse lemur primate brain

CLEMENT GARIN1,2, NACHIKET ABHAY NADKARNI 1,2, JEAN-LUC PICQ1,2, SALMA BOUGACHA 1,2, and MARC DHENAIN1,2

1Commissariat à l’Energie Atomique et aux Energies Alternatives (CEA), Direction de la Recherche Fondamentale (DRF), Institut François Jacob, MIRCen, Fontenay-aux-Roses, France, 2Centre National de la Recherche Scientifique (CNRS), Université Paris-Sud, Université Paris-Saclay UMR 9199, Neurodegenerative Diseases Laboratory, Fontenay-aux-Roses, France

Resting state networks have been characterized in numerous mammals covering human, non-human primates, dogs, rabbits and rodents, though only ever at single semi-arbitrary levels of complexity. In humans, resting state networks analyses have been extended to extracting networks of varying complexity, representing different levels of a possible “functional hierarchy”. We performed the first study of “functional hierarchy” in animals. We focused on the gray mouse lemur (Microcebus murinus), a small primate attracting increased attention as a model for cerebral and age-related disorders.

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