Abstract #0886

Functional connectivity predicts individual longitudinal development in inhibitory control ability: a 5-year follow-up study

Haiyan Wang^1,2,3, Lingzhong Fan^1,3, Dongya Wu^1,2,3, and Tianzi Jiang^1,2,3,4,5,6

¹Brainnetome Center, Institute of Automation, Chinese Academy of Sciences, Beijing, China, ²National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing, China, ³University of Chinese Academy of Sciences, Beijing, China, ⁴CAS Center for Excellence in Brain Science and Intelligence Technology, Institute of Automation, Chinese Academy of Sciences, Beijing, China, ⁵The Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for Neuroinformation, University of Electronic Science and Technology of China, Chengdu, China, ⁶The Queensland Brain Institute, University of Queensland, Brisbane, Australia

Inhibitory control ability (IC) is related to adolescence impulsive and risky behaviors. It will develop into adulthood, but its trajectory has great individual difference. What brain features affect the individualized development of IC? Here we use longitudinal data and predictive model to predict stop signal reaction time (SSRT) change in 5 years with 14-year-old stop signal task functional connectivity (FC). We find that 14-year-old FCs between ventral attention and subcortical networks can predict the development tendency of IC, even excluding the effect of 14-year-old SSRT. This may help to make early intervention in the development of adolescent IC.

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