Abstract #0481

Dynamic 31P MRS of Skeletal Muscle with a 1 Telsa Extremity Scanner

Minyu Gu¹, Travis Carrell², John Bosshard³, Clayton L. Cruthirds^4,5, Nicolaas E.P. Deutz^4,5, Marielle PKJ Engelen^4,5, Mary P. McDougall², and Steven M. Wright¹

¹Electrical & Computer Engineering, Texas A&M University, College Station, TX, United States, ²Biomedical Engineering, Texas A&M University, College Station, TX, United States, ³Electronic Systems Engineering Technology, Texas A&M University, College Station, TX, United States, ⁴Department of Health & Kinesiology, Texas A&M University, College Station, TX, United States, ⁵Center for Translational Research on Aging and Longevity, Texas A&M University, College Station, TX, United States

The potential of using low-field MRI scanners as a platform to enable low-cost 31P studies outside of the conventional hospital environment was examined. All experiments were conducted on an ONI 1T scanner with a custom broadband multichannel receiver. A transmit-only birdcage and receive-only four-element array were designed and built to enhance the SNR and improve linewidth. Preliminary phantom and in vivo results show the proposed design improved the linewidth from 0.71 ppm to 0.33 ppm, SNR was increased by approximately 2 times, and inorganic phosphate and phosphocreatine exchange were observed during the volunteer’s exercise.

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