This study examined the reproducibility of calf-muscle perfusion measurements from DCE-MRI following plantar-flexion exercise, which is a promising technique for assessing calf-muscle function and viability. In a group of healthy subjects, the same post-exercise DCE-MRI protocol was repeated on two different days and calf-muscle perfusion measurements were compared between the two visits. High correlation and agreement of perfusion between visits was observed for the posterior calf muscles, demonstrating that a plantar-flexion exercise protocol followed by DCE-MRI is suitable for achieving precise measurements of calf-muscle perfusion.
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