Abstract #5109

APT-CEST post Gadolinium. Should it be avoided? Comparison of pre- & post-Gadolinium CEST on glioma at 3T.

Francisco Torrealdea¹, Joe Hearle², Vincent Evans¹, Moritz Zaiss³, Ana Carvalho⁴, Anath Shankar⁵, Harpreet Hyare⁴, David Atkinson¹, Xavier Golay⁴, Anna Barnes⁴, and Marilena Rega⁴

¹Centre for Medical Imaging, UCL, london, United Kingdom, ²Medical school, UCL, london, United Kingdom, ³High Field Magnetic Resonance, Max Plank Institute, Tubinghen, United Kingdom, ⁴Institute of Nuclear Medicine, UCLH, London, United Kingdom, ⁵Teenage Cancer Unit, UCLH, london, United Kingdom

This study compares APT-CEST between pre- and post-gadolinium in patients with gliomas at 3T, and evaluates the feasibility of performing CEST after administration of T1 contrast. The results of the study demonstrate that Gd administration does not significantly affect the quality of the APT-CEST image, encouraging the acquisition of CEST data, even after the administration of T1 contrast agents.

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