Abstract #4832

Cerebrovascular resistance responses to CO2 improve after revascularization surgery

Larissa McKetton¹, Olivia Sobczyk², Julien Poublanc¹, Kevin Sam³, Adrian P. Crawley¹, Lakshmikumar Venkat Raghavan⁴, James Duffin^4,5, Joseph A. Fisher^2,4,5, and David J. Mikulis^1,4,5

¹Division of Neuroradiology, Joint Department of Medical Imaging, University Health Network, Toronto, ON, Canada, ²Institute of Medical Science, University of Toronto, Toronto, ON, Canada, ³The Russell H. Morgan Department of Radiology & Radiological Science, The John Hopkins University School of Medicine, Baltimore, MD, United States, ⁴Department of Anaesthesia and Pain Management, University Health Network, Toronto, ON, Canada, ⁵Department of Physiology, University of Toronto, Toronto, ON, Canada

The cerebral hemodynamics of patients undergoing revascularization surgery for intracranial steno-occlusive disease (IC-SOD) were assessed by deriving an estimate of their cerebrovascular resistance response to CO₂ from their BOLD response to CO₂. Significant improvements were found in the sigmoid parameters describing their resistance responses.

This abstract and the presentation materials are available to members only; a login is required.

Join Here