In 23Na MRI it is possible to selectively detect signal from sodium ions bound to anisotropic structures by applying a double quantum filter with magic angle excitation (DQ-MA). In this work, the influence of B0-inhomogeneities on the DQ-MA filtering capacity was examined both theoretically and experimentally. We found that under practical conditions (|ΔB0| ≈ 50 Hz at 3T) a significant amount of unwanted odd rank double quantum coherence signal may pass the filter even in case of perfect magic angle excitation. Therefore, B0-inhomogeneities may cause an over-estimation of the degree of anisotropy.
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