Abstract #3771

Fluid and White Matter Suppression sequence for detecting epileptogenic zones of focal cortical dysplasia

Xin Chen¹, Tianyi Qian², Tobias Kober^3,4,5, Nan Chen¹, and Kuncheng Li¹

¹Radiology, Xuanwu Hospital, Capital Medical University, Beijing, China, ²MR Collaborations NE Asia, Siemens Healthcare, Beijing, China, ³Advanced Clinical Imaging Technology (HC CMEA SUI DI PI), Siemens Healthcare AG, Lausanne, Switzerland, ⁴Radiology, University Hospital (CHUV), Lausanne, Switzerland, ⁵LTS5, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland

The aim of this study was to evaluate a novel sequence, called the fluid and white matter suppression (FLAWS) sequence, for detecting focal cortical dysplasia (FCD) lesions. FLAWS provides two sets of 3D contrast images from one acquisition and subsequently calculates another set of images that can suppress the signal from both the cerebral spinal fluid and white matter. The detection rate of the FCD lesions on FLAWS was higher than on the conventional 2D MR scan and 3D fluid-attenuated inversion recovery scan. Additionally, the transmantle sign, which is widely believed to be speciﬁc for FCD type II, could also be observed in FCD type I on the FLAWS images.

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