In this study we propose to further improve the precision of free-breathing 3D saturation-recovery based T1 mapping (3D SASHA), while keeping its high accuracy, by employing a novel 3D denoising method which exploits spatio-temporal correlations in the T1-weighted images. The proposed approach has been tested on ten healthy subjects and four patients with cardiovascular disease. For all subjects, no statistical difference was observed between the precision measured on 3D denoised SASHA and 2D MOLLI T1 maps (p=0.62), while preserving the T1 accuracy. There was an improvement in the precision after denoising on the 3D SASHA T1 maps acquired in healthy subjects and patients.
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