In this study we propose to accelerate the 3D saturation-recovery (3D SASHA) T1-mapping technique by using a reduced number of saturation time points while maintaining accuracy and precision using a 3D denoising method. No statistical difference was found in terms of accuracy and precision (respectively p=0.14 and p=0.99) between the T1-maps reconstructed after denoising using different number of T1-weighted images (between three and nine). After application of 3D denoising, the precision was independent of the number of T1-weighted images used for the fitting, which may permit to considerably accelerate the 3D SASHA acquisition.
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