Cardiac diffusion tensor imaging (cDTI) is a novel non-invasive method that allows assessing changes in myocardial microstructure in various cardiomyopathies. To identify pathologies, however, the distribution of cDTI parameters and their subject specific dependencies in normal hearts need to be known. Therefore, we investigated age, gender and heart rate dependencies of quantitative parameters derived from spin-echo based cDTI in healthy subjects. Our results display the variation of cDTI parameters in normal hearts and thereby allow gauging at which level of expected pathological changes sex and age matched reference values will be needed in future clinical practice.
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