The retinal vascular fractal dimension (FD) is a marker of retinal vascular complexity of the vascular tree. It has been associated with systemic disorders but also with neurodegenerative and cerebrovascular diseases. The purpose of this study was to explore the relationship between cerebral blood flow (CBF), retinal vascular FD and other retinal vascular markers. CBF was estimated in vascular territories using 2D PASL sequence. CBF was positively associated to venular FD (R2=0.32, p=0.03). Non-invasive exploration of the retinal vasculature may be used as a proxy measure, with the condition of retinal vessels possibly reflecting the condition of the cerebral vasculature.
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