We selected ADNI patients with an initial diagnosis of mild cognitive impairment (MCI) due to early Alzheimer’s disease, a positive amyloid PET scan within 4 years, and comparable cognitive test scores during their initial visit. Patients were grouped according to their diagnosed outcome within 4 years of the initial visit, specifically, MCI subsequently diagnosed with dementia and stable MCI. We found that curvature within the temporal lobe was greater among patients subsequently diagnosed with dementia. Established measurements of atrophy, including hippocampal volume and temporal lobe thickness, did not differ between these groups.
This abstract and the presentation materials are available to members only; a login is required.