Abstract #1813

Resting-state brain functional alteration in dorsal attention network associated with post-chemotherapy breast cancer

Chao-Yu Shen^1,2,3, Vincent Chin-Hung Chen^4,5, Xuan-Ru Zhang², Meng-Syuan Lin², Dah-Cherng Yeh⁶, Yeu-Sheng Tyan^2,3, Ming-Chih Chou^1,7, and Jun-Cheng Weng^5,8

¹Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan, ²Department of Medical Imaging and Radiological Sciences, Chung Shan Medical University, Taichung, Taiwan, ³Department of Medical Imaging, Chung Shan Medical University Hospital, Taichung, Taiwan, ⁴School of Medicine, Chang Gung University, Taoyuan, Taiwan, ⁵Department of Psychiatry/ Health Information and Epidemiology Laboratory, Chang Gung Memorial Hospital, Chiayi, Taiwan, ⁶Breast Center, Taichung Tzu Chi Hospital, Taichung, Taiwan, ⁷Division of Thoracic Surgery, Department of Surgery, Chung Shan Medical University Hospital, Taichung, Taiwan, ⁸Department of Medical Imaging and Radiological Sciences, Chang Gung University, Taoyuan, Taiwan

The current study was to investigate post-chemotherapy breast cancer with rs-fMRI using mfALFF analysis and correlated with clinical cognitive testing. The results showed altered brain activity in the dorsal attention network in breast cancer patients compared to healthy controls and the affected areas were associated with MMSE, CAMS-R and IES-R scores.

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