In the presented study we've demonstrated that small changes in Glutamate concentration associated with performing simple motor task can be reliably detected with 3T system using functional 1H MR spectroscopy. Comparison between two differently timed paradigms for motor activation revealed a clear preference for longer-block designs. This suggests that motor activity-induced changes in Glutamate concentration are of minutes-long time-scale.
This abstract and the presentation materials are available to members only; a login is required.