We present a cross sectional study of 53 subjects with chronic lower back pain (n=39) and healthy controls (n=14). We have assessed disc biochemical composition (T1rho and T2 mapping) and vertebral bone marrow fat (6-point chemical-shift based imaging) as well as Pfirrmann grading. We have found significant associations between mean and standard-deviation of T1rho and T2 with vertebral bone marrow fat content in the adjacent vertebral body. We have also found strong associations of T1rho and T2 with clinical Pfirrmann grading.
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