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Abstract #0460

T1ρ and T2 of articular cartilage and medial meniscus at baseline and 6-month can predict the degenerative changes of cartilage at 3 years after ACL reconstruction

Kenji Mamoto1,2, Kaipin Xu1,2, Tomohiro Shimizu2, Matthew Tanaka2, Alexander Markes2, Valentina Pedoia2, C. Benjamin Ma3, and Xiaojuan Li1,2

1Biomedical Engineering, Cleveland Clinic, Cleveland, OH, United States, 2Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, United States, 3Orthopedic Surgery, University of California, San Francisco, San Francisco, CA, United States

Patients with anterior cruciate ligament (ACL) injury have a high risk of development of early post-traumatic osteoarthritis (PTOA) even after ACL reconstruction. The aim of this study was to investigate the risk factors that may predict the longitudinal cartilage degeneration by using MR T1ρ/T2 imaging. The first 6-month changes of T1ρ/T2 values of the cartilage and anterior horn of medial meniscus significantly correlated with the 3-year cartilage degenerative change after ACL reconstruction. And also, T2 values of the posterior horn of medial meniscus prior to surgery significantly correlated with the cartilage degeneration of anterior medial tibia 3-year after the reconstruction.

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