Abstract #0287

High resolution in-vivo diffusion tensor cardiovascular magnetic resonance: a comparison of single-shot EPI and interleaved spiral trajectories with motion induced phase correction

Margarita Gorodezky^1,2, Andrew David Scott^1,2, Pedro F Ferreira^1,2, Sonia Nielles-Vallespin^1,2,3, Peter D Gatehouse^1,2, Dudley J Pennell^1,2, and David N Firmin^1,2

¹Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, London, United Kingdom, ²National Heart and Lung Institute, Imperial College, London, United Kingdom, ³National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, United States

The spatial resolution of DT-CMR STEAM acquisitions was increased by implementing an interleaved variable density spiral readout. Bulk motion during STEAM diffusion encoding is unavoidably encoded in the image phase which can result in signal loss for multi-shot acquisition when the multiple interleaves are combined. A phase correction was implemented using the fully sampled centres of k-space to calculate the differences in phase between interleaves. In 7 volunteers we show improved data quality at 2.0x2.0mm² using interleaved spirals compared to single-shot EPI and we obtain similar DT-CMR parameters.

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