Abstract #0286

Cardiac Phase-resolved Late-Gadolinium Enhancement Imaging

Sebastian Weingärtner^1,2,3, Burhaneddin Yaman^1,2, Chetan Shenoy⁴, Marcel Prothmann⁵, Felix Wenson⁵, Jeanette Schulz-Menger^5,6, and Mehmet Akcakaya^1,2

¹Electrical and Computer Engineering, University of Minnesota, Minneapolis, MN, United States, ²Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States, ³Computer Assisted Clincial Medicine, Heidelberg University, Mannheim, Germany, ⁴University of Minnesota, Minneapolis, MN, United States, ⁵Working Group on Cardiovascular Magnetic Resonance Imaging, Max-Delbrück-Centrum and Charité -Medical University Berlin, Berlin, Germany, ⁶Department of Cardiology and Nephrology, HELIOS Klinikum Berlin-Buch, Berlin, Germany

Late Gadolinium Enhancement (LGE) is commonly acquired during a single end-diastolic phase with inversion-recovery contrast that nulls healthy myocardial tissue. In this work, we propose a method for acquisition of cardiac phase-resolved LGE images based on an ECG triggered Look-Locker experiment with continuous FLASH imaging. Semi-quantitative evaluation of this pulsed-inversion recovery allows synthetization of LGE image contrast for all cardiac phases. Accurate functional depiction with temporal resolution up to 60 ms is obtained in healthy subjects at 3T. Images of 20 patients on a clinical 1.5T scanner show promising depiction of focal scar at a temporal resolution of 80ms.

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