Brain iron is critical for neural processes implicated in addiction. Recently, disrupted iron regulation was detected in individuals with cocaine use disorder (CUD) using quantitative susceptibility mapping. Our goal was to replicate these findings using an alternative iron imaging method called magnetic field correlation imaging. Consistent with the only study of brain iron in CUD, we detected elevated brain iron levels in globus pallidus regions and loss of age-related iron accumulation in CUD. Our replication of aberrant brain iron findings in CUD using a different MRI modality lends support for further investigation of iron homeostasis in CUD.
This abstract and the presentation materials are available to members only; a login is required.