Repetitive and noninvasive MR examinations of fat content can provide indispensable information for longitudinal metabolic studies. It is of great interest to understand how obesity in youth affects the fat metabolism later in life. Thus we longitudinally examined mice with/without a high-fat diet [HFD] for 8 weeks from 13 to 67 weeks old using MRI and 1H MRS. As a result, visceral fat restored normalcy in 10 weeks after the termination of HFD, subcutaneous and liver fat returned to normalcy in ~ 16 - 20 weeks as compared to controls.
This abstract and the presentation materials are available to members only; a login is required.