Abstract #5342

Detection of Functional Activity in Somatosensory Pathways Using Tactile Stimulations

Xi Wu^1,2, Zhipeng Yang^1,2, Stephen K. Bailey³, Jiliu Zhou¹, Laurie C. Cutting^4,5, John C. Gore^2,5,6, and Zhaohua Ding^2,6,7

¹Department of Computer Science, Chengdu University of Information Technology, Chengdu, People's Republic of China, ²Vanderbilt University Institute of Imaging Science, Nashville, TN, United States, ³Brain Institute, Vanderbilt University, Nashville, TN, United States, ⁴Vanderbilt Kennedy Center, Vanderbilt University, Nashville, TN, United States, ⁵Department of Radiology and Radiological Science, Vanderbilt University Medical School, Nashville, TN, United States, ⁶Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, United States, ⁷Department of Electrical Engineering and Computer Science, Vanderbilt University, Nashville, TN, United States

Functional magnetic resonance imaging has been widely used in measuring functional connectivity between cortical regions, but it has not been well-established in white matter to date. While we have previously demonstrated that resting state BOLD signals exhibit structure-specific correlations, suggesting that neural activities may be encoded in white matter BOLD signals as well, in this study we further confirm that functional stimulations can induce activities in relevant white matter pathways.

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