Abstract #5214

Fluid and white matter suppression (FLAWS) with MP2RAGE sequence at 7T.

Yuta Urushibata¹, Hideto Kuribayashi¹, Junko Inoue¹, Tobias Kober^2,3,4, John Grinstead⁵, and Tomohisa Okada⁶

¹Siemens Healthcare K.K., Tokyo, Japan, ²Advanced Clinical Imaging Technology, Siemens Healthcare AG, Lausanne, Switzerland, ³Department of Radiology, University Hospital (CHUV), Lausanne, Switzerland, ⁴LTS5, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, ⁵Siemens Medical Solutions, Inc., United States, ⁶Kyoto University, Kyoto, Japan

Fluid and white matter suppression (FLAWS) is a technique to suppress cerebrospinal fluid (CSF) and white matter (WM) using the MP2RAGE sequence, which has been introduced for 3T. In this study, FLAWS was applied at 7T and compared to a SPACE double inversion recovery (DIR). Inversion times of the sequences were optimized for volunteer brain images at 7T. FLAWS showed better suppression of CSF and WM, more homogeneous gray matter (GM) delineation, as well as better GM/WM contrast compared with DIR.

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